ar-a 2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10360	AR-A 2	AR-A 000002	Others
	AR-A 2 is a selective 5-HT1B receptor antagonist, with a high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM) and with 10-fold lower affinity to guinea pig 5-HT1D...		Others
T28046	Mirosamicin	A 11725 II,Antibiotic AR 5-2
	Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.
T60924	Verosudil	AR-12286	ROCK
	Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 reverses steroid-induced intraocular pressure in mice by decreasing intraocular ...		ROCK
T36375	Ralaniten triacetate
	Ralaniten triacetate (EPI-506) is a novel pro-drug of Ralaniten, functioning as an orally active inhibitor of the androgen receptor (AR) N-terminal domain (NTD). Its remarkable first-in-class status signifies its unique ...
T9179	CLP-3094	2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE	Androgen Receptor
	CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GP...		Androgen Receptor
T14315	AR-9281	APAU	Epoxide Hydrolase
	AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes		Epoxide Hydrolase
T27439	GS-9667	CVT-3619,CVT 3619	Adenosine Receptor
	GS-9667, a selective and partial agonist of the A(1) adenosine receptor (AR), represents an effective therapy for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA).		Adenosine Receptor
T22489	2'-MeCCPA	2-Chloro-N-cyclopentyl-2′-C-methyladenosine	HCV Protease , Adenosine Receptor
	2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM.2'-MeCCPA ...		HCV Protease , Adenosine Receptor
T0371	Gliquidone	AR-DF 26,Glurenorm	Potassium Channel
	Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding affinity to SUR1 and increased potency compared...		Potassium Channel
T3046	BMY 7378 dihydrochloride	BMY7378 HCl	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T6422	Brimonidine Tartrate	AGN190342 tartrate,304 tartrate,AGN190342 (tartrate),UK 14304 (tartrate),UK14304 tartrate	Adrenergic Receptor
	Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hyperten...		Adrenergic Receptor
T22245	Arformoterol Tartrate	(R,R)-Formoterol tartrate	Adrenergic Receptor
	Arformoterol Tartrate ((R,R)-Formoterol tartrate) is the tartrate salt of arformoterol. Arformoterol is a long-acting beta-2 adrenergic agonist with bronchodilator activity[2].		Adrenergic Receptor
T21395	Finerenone	BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862	Glucocorticoid Receptor
	Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862...		Glucocorticoid Receptor
T60677	Dobutamine
	Dobutamine is a synthetic catecholamine that can increase cardiac output and correct hypoperfusion. Dobutamine acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors) that is a selective agonist of β1-AR , relatively...
T11804	β3-AR agonist 2		Others
	β3-AR agonist 2 is a potent and selective agonist of β3-adrenergic receptor (β3-AR with an EC50 of 8 nM).		Others
T63030	AR antagonist 2
	AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).
T14317	ar-Turmerone	(+)-ar-Turmerone	Others
	ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on mur...		Others
T62018	Adenosine receptor inhibitor 2
	Adenosine receptor inhibitor 2 (compound 14b) is a potent inhibitor of AR (adenosine receptor). Adenosine receptor inhibitor 2 exhibits dual affinity toward A 1 /A 2A ARs with higher affinity for the A 1 - than the A 2A ...
TCS2185	Yohimbine		Adrenergic Receptor
	Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM)		Adrenergic Receptor
T62951	Aldose reductase-IN-2
	Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR) with antioxidant properties. aldose reductase-IN-2 is a promising anti-diabetic complication drug.